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NCLEX Med-Surg Practice Questions

Free medical-surgical nursing practice questions covering the conditions, prioritization, and interventions the NCLEX-RN loves to test — with detailed rationales.

Question 1Multiple choiceMed-Surg

A client's potassium is 6.8 mEq/L. Which ECG change does the nurse expect to see first?

  1. ST depression and prominent U waves
  2. Tall, peaked T waves
  3. Prolonged QT interval
  4. Widened QRS with a normal T wave
Show answer & rationale

Correct: Tall, peaked T waves

Why: Hyperkalemia's earliest ECG sign is tall, peaked T waves, progressing to prolonged PR, widened QRS, and finally a sine-wave pattern leading to arrest. ST depression with prominent U waves plus muscle weakness is the mirror image — hypokalemia. Memory aid: hyperkalemia's peaked T waves look like tents — 'K+ pitches a tent'.

📚 Basis: Normal serum K+ 3.5–5.0 mEq/L; hyperkalemia ECG progression: peaked T waves → widened QRS → sine wave. · AHA cardiac arrhythmia guidance

Question 2Multiple choiceMed-Surg

A client has a chest tube after a pneumothorax. Which finding requires immediate nursing action?

  1. Tidaling in the water-seal chamber with respirations
  2. Continuous vigorous bubbling in the water-seal chamber
  3. Small amount of serosanguineous drainage in the collection chamber
  4. Client reports mild pain at the insertion site
Show answer & rationale

Correct: Continuous vigorous bubbling in the water-seal chamber

Why: Continuous vigorous bubbling in the water-seal chamber means air is leaking into the system — check for loose connections or a lung leak and fix it. Tidaling (fluid level rising and falling with breathing) is normal and expected. A small amount of serosanguineous drainage is normal early on; sudden large-volume or bright-red drainage is the concerning pattern. Memory aid: continuous bubbling means a leak somewhere — 'bubbles spell trouble'.

📚 Basis: Water-seal chamber: tidaling with respirations = patent system; continuous bubbling = air leak. · Standard thoracic drainage references

Question 3Multiple choiceMed-Surg

A client in DKA has a blood glucose of 520 mg/dL and is dehydrated. The nurse's first IV fluid action is to infuse:

  1. D5W at 125 mL/hr
  2. 0.9% sodium chloride wide open per protocol
  3. 0.45% sodium chloride at maintenance rate
  4. D5 0.45% NaCl at 75 mL/hr
Show answer & rationale

Correct: 0.9% sodium chloride wide open per protocol

Why: DKA causes profound osmotic diuresis and volume depletion, so resuscitation starts with isotonic crystalloids (0.9% NaCl or lactated Ringer's) wide open per protocol to restore perfusion. Dextrose is added only after glucose falls to ~250 mg/dL, so insulin can keep clearing ketones without causing hypoglycemia. Memory aid: DKA is dry — fill the tank with isotonic fluids before chasing the sugar.

📚 Basis: ADA DKA management: aggressive isotonic fluid resuscitation first; add dextrose when glucose falls to ~250 mg/dL. · ADA Standards of Care (DKA)

Question 4Multiple choiceMed-Surg

A client with SIADH has a serum sodium of 122 mEq/L. The nurse's priority intervention is to:

  1. Encourage oral fluids to 3 liters per day
  2. Restrict fluids per provider order
  3. Administer hypotonic IV fluids
  4. Encourage a high-sodium diet without limits
Show answer & rationale

Correct: Restrict fluids per provider order

Why: SIADH means excess ADH → water retention → dilutional hyponatremia. Treatment is fluid restriction (commonly 800–1,000 mL/day) plus addressing the cause. Giving free water or hypotonic fluids dilutes sodium further and risks worsening cerebral edema. Memory aid: SIADH means 'soaked inside' — too much retained water dilutes sodium, so restrict fluids.

📚 Basis: SIADH: euvolemic hypo-osmolar hyponatremia from excess ADH; first-line treatment is fluid restriction. · Endocrine Society hyponatremia guidance

Question 5Multiple choiceMed-Surg

Using the Parkland formula, the 8-hour fluid requirement for a 70-kg client with 40% TBSA burns is:

  1. 2,800 mL
  2. 5,600 mL
  3. 11,200 mL
  4. 1,400 mL
Show answer & rationale

Correct: 5,600 mL

Why: Parkland: 4 mL × kg × %TBSA = 4 × 70 × 40 = 11,200 mL over 24 hours. Half (5,600 mL) is given in the first 8 hours post-burn, the rest over the next 16 hours. Titrate to urine output (0.5–1 mL/kg/hr in adults). Memory aid: 4 mL × kg × %burn, half in the first 8 hours — 'four for the floor, half in eight'.

📚 Basis: Parkland formula: 4 mL × kg × %TBSA per 24 h; half in first 8 h post-burn. · American Burn Association guidance

Question 6Multiple choiceMed-Surg

Before administering a blood transfusion, the nurse's priority verification step is to:

  1. Check the client's temperature
  2. Verify client identity with two identifiers and match the blood unit at the bedside with a second nurse
  3. Flush the line with dextrose
  4. Premedicate with diphenhydramine
Show answer & rationale

Correct: Verify client identity with two identifiers and match the blood unit at the bedside with a second nurse

Why: Fatal hemolytic reactions come from ABO mismatch, so two-nurse bedside verification with two client identifiers matched to the unit tag is the critical step. Blood infuses with normal saline only — dextrose causes hemolysis, and the calcium in lactated Ringer's can clot the blood. Memory aid: blood only likes normal saline — 'NS is blood's best friend'.

📚 Basis: AABB: two-identifier + two-nurse bedside verification; normal saline only with blood products. · AABB transfusion standards

Question 7Select all that applyMed-Surg

The nurse is teaching a client with heart failure about warning signs of fluid overload. Which findings should the client report immediately? Select all that apply.

  1. Weight gain of 3 lb in 24 hours
  2. Crackles heard in the lung bases
  3. Decreased urine output
  4. Pink, frothy sputum
  5. Increased appetite
  6. Visible neck vein distention when sitting upright
Show answer & rationale

Correct: Weight gain of 3 lb in 24 hours; Crackles heard in the lung bases; Decreased urine output; Pink, frothy sputum; Visible neck vein distention when sitting upright

Why: Heart failure exacerbation = fluid overload: rapid weight gain (2–3 lb in a day or 5 lb in a week), bibasilar crackles, oliguria, pink frothy sputum (pulmonary edema), and jugular vein distention. Increased appetite is the trap — these clients typically report anorexia and early satiety, not hunger. Memory aid: 2–3 lb overnight or 5 in a week — 'a few pounds means call the provider'.

📚 Basis: HF fluid-overload signs; daily weights — report 2–3 lb gain in 24 h or 5 lb in a week. · AHA/ACC/HFSA heart failure guidelines

Question 8Select all that applyMed-Surg

The nurse is planning care to prevent deep vein thrombosis in a post-operative client. Which interventions are appropriate? Select all that apply.

  1. Early ambulation as tolerated
  2. Sequential compression devices while in bed
  3. Ankle pump and leg exercises
  4. Encouraging adequate fluid intake
  5. Keeping the client on strict bed rest
  6. Crossing the legs at the knees
Show answer & rationale

Correct: Early ambulation as tolerated; Sequential compression devices while in bed; Ankle pump and leg exercises; Encouraging adequate fluid intake

Why: Virchow's triad (stasis, hypercoagulability, endothelial injury) drives DVT: ambulation, SCDs, leg exercises, and hydration all reduce stasis. Prolonged bed rest and crossing the legs promote venous stasis. Memory aid: Virchow's triad — stasis, sticky blood, scratched vessel.

📚 Basis: DVT prevention targets Virchow's triad (stasis, hypercoagulability, endothelial injury); mobility + mechanical measures reduce stasis. · CHEST VTE prevention guidelines

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NCLEX Drill offers practice questions for study purposes only — not medical advice, and not a substitute for professional judgment or official study materials. Question bank grows daily; last updated 2026-10-09.